“Significant” is an interesting choice of words, but AC Immune makes a lot of sense for several reasons. The Dr. Lowe connection is big since he is so familiar with Elto.

Dr. Lowe’s bio doesn’t even mention Amarantus. Maybe that’s a bad sign...

https://www.acimmune.com/en/senior-management-team/

Did we ever hear anything about the circumstances surrounding his exit?