Cause and effect being confused once again. Why do they always start from the assumption that tau and amyloid plaques are CAUSE and not EFFECT of Alzheimer's?

Quote:

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the understanding of exactly how these proteins interact to cause dementia is still largely a mystery.
....
Drugs that target amyloid plaques have been disappointing in Alzheimer’s. Witness the failures of Eli Lilly’s solanezumab and Merck’s verubecestat. But scientists who study Alzheimer’s have not given up on the notion that preventing the protein from building up in the brain could be an effective way of preventing the descent into memory loss.

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The whole article is well worth reading.

https://www.fiercebiotech.com/research/stem-c...d=48083647