"The hyperproliferative diseases that may be treated by the methods of the present invention include, but are not limited to, cancer of the breast, bladder, bone, brain, central and peripheral nervous system, colon, endocrine glands, esophagus, endometrium, germ cells, head and neck, kidney, liver, lung, larynx and hypopharynx, mesothelioma, sarcoma, ovary, pancreas, prostate, rectum, small intestine, soft tissue, testis, stomach, skin, ureter, vagina and vulva; inherited cancers, retinoblastoma and Wilms tumor; leukemia, lymphoma, non-Hodgkins disease, chronic and acute myeloid leukemia, acute lymphoblastic leukemia, Hodgkins disease, multiple myeloma and T-cell lymphoma; myelodysplastic syndrome, plasma cell neoplasia, paraneoplastic syndromes, cancers of unknown primary site, drug resistant cancers and AIDS related malignancies and the disease is treated by administering to a mammal in need of such treatment an antihyperproliferation or anticancer effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof. In one embodiment of the invention, the hyperproliferative disease is selected from the group consisting of head and neck cancer, non-small cell lung cancer, small cell lung cancer, resistant types of lung and any female cancers, breast cancer, ovarian cancer and colon cancer. "