$CBIS Suppositories are 50% to 70% more efficient and produce a more predictable effect than smoked or ingested cannabis. The rectal endothelium provides greater bioavailability than transcutaneous and oral delivery of cannabinoids. Suppositories can also be more effective in treating pelvic and lower gastrointestinal conditions. Additionally, suppositories are effective in individuals with nausea and vomiting, those with difficulty in swallowing pills (the elderly), those with wasting conditions especially in cases where appetite is inhibited, and in individuals on chemotherapy who find it difficult to manage oral medications.

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