I am a little concerned about the negative trend that has formed over the last 2 months. Product to market, Large JV partner, or approval for orphan study are the only things that will break us out of this trend. I don't even think that the efficiency results or secured patents at this point will do it. Might eliminate some of the doubt. Bought a little more to lower my average pps but also buying other stocks now. I've been hanging on through the worst of it so far but it's getting harder to wait out. We need to see management executing at a high level and we need perspective into their business plan for this year. I think shareholder calls would be a great thing as well to help rebuild some of the trust OWCP seems to have lost.