I can't help but laugh, I'm sorry if someone is afflicted with a condition requiring a suppository. I once was so drunk and hungover that I was treated by my best friends mom with a suppository....and damn if it didn't work magic!! Of course that was 25 years ago....the psoriasis cream as identified in the latest 8, states only 7.5 million suffer in the US....worldwide, I'm guessing 40 million lets say......that alone doesn't get us to $20 this year imo... just trying to keep everyone grounded....I hope for $4 on efficacy news