$ACXA Our BranchPoint Device

Our BranchPoint device can deliver therapeutics through the radial deployment of a flexible delivery catheter to large and anatomically complex brain targets through a single initial brain penetration. Clinicians can "tailor" thera-peutic delivery to individual patient anatomy and specific disease targets, which may enhance the efficacy of therapies. Our BranchPoint device may also give physicians more precise control of the volume of therapeutics delivered and ensure that therapeutics delivered into the brain stay in the brain, avoiding the problem of reflux out to the brain surface. This modern and "easy to use" technology may allow "real-time" monitoring of therapeutic delivery under interventional MRI guidance (iMRI), which could improve the accuracy of therapeutic delivery, reduce the risk of complications, and increase patient safety.



Currently available neurosurgical devices can deliver a straight, rigid needle to single brain locations. However, this basic strategy limits the size and "shape" of the brain treatment area. In order to deliver to larger and more complex brain targets, the surgeon needs to penetrate the brain multiple times with such straight needles, which may increase the risk of bleeding and stroke, and may reduce the efficacy of therapeutics due to reflux, whereby therapeutics injected using straight needles can flow back out to the brain surface along the needle's path.

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