Due to Brilacidin's unique MOA, bacteria are unlikely to develop resistance to it. The human body has been using defensins against bacteria for thousands of years without resistance developing. After all, what are bacteria going to do, start growing little Kevlar vests?

Brilacidin is the beginning of a new paradigm in the field of antibiotics. Traditional antibiotics will most likely be relegated to the dustbin of history as defensins memetics become the primary drugs used in the war against disease causing bacteria.

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The whole idea of having a new anti-bacterial drug of "last resort" is carefully restrict its use for the really bad bugs. If it goes it into everyday use for things like shaving cream and hand soap, the quicker some bacteria will develop a resistance to it. It will end up in the "useless" basket like so many other former wonder drubs. Just my opinion. - windansea