These biotechs go up and down and rarely trade for what they are actually worth- sometimes they trade for alot more than they are worth and sometimes for a lot less than they are worth (as is the case with AMBS right now), but they are NOT long term holds- meaning several years or more. I bought TTNP a few years ago for .70. It ran to $2.50, but I didn’t sell. It drifted back to $1.70 and then they received a CRL form the FDA. It opened the next day in the .30’s. I sold for a loss. Since that time TTNP did a RS , uplisted to the FDA and got FDA approval- yet the market cap is only a third of what it was during the run-up a few years ago.

Imagine if AMBS were to run to a $1.00. Would you actually make the decision to hold for more? You’ve made 20 times what you can buy it for today, but you say to yourself, no I will wait to make 50 times my money. See how crazy that sounds? Don’t be greedy or foolish. Even if they received $50 million tomorrow and the price skyrocketed, (which is when you would want to sell) they would still need to do more financings in the future, more dilutions etc.- the price would go back down at some point (which could be another opportunity to buy back in). I would try to get my average below a $1.00 if possible. If you are unwilling to take the risk to do that, then I would sell for what I could get on the next run-up and move on with the loss, otherwise you will be taking just as big a risk waiting for more money to come later when you could have taken the funds and invested in another stock and made your money back there instead.