Posted On: 07/27/2016 5:53:56 PM
Post# of 72446
No answer from Leo this time. But based on slide 22 of the Dermatology Overview, I'm fairly sure that the answer is closer to 83% than 25%.
"AUC values were comparable for both Prurisol and Ziagen, within 80% to 125% equivalence window, indicating equivalent systemic exposure."
http://cellceutix.com/wp-content/uploads/2014...16-1-1.pdf
"In the field of pharmacokinetics, the area under the curve (AUC) is the area under the curve (mathematically known as definite integral) in a plot of concentration of drug in blood plasma against time."
https://en.wikipedia.org/wiki/Area_under_the_...okinetics)
"AUC values were comparable for both Prurisol and Ziagen, within 80% to 125% equivalence window, indicating equivalent systemic exposure."
http://cellceutix.com/wp-content/uploads/2014...16-1-1.pdf
"In the field of pharmacokinetics, the area under the curve (AUC) is the area under the curve (mathematically known as definite integral) in a plot of concentration of drug in blood plasma against time."
https://en.wikipedia.org/wiki/Area_under_the_...okinetics)
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Let me know if you decide to verify that with Cellceutix. That would be extremely valuable toward answering a specific question I have.
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