Looks like moderate to severe psoriasis may be the best use. Also, it's dose-dependent -- the highest dose was the one that worked -- and the results improve over time. Results started really showing after 8 weeks.

So, it looks like higher doses, and longer dosing times are the next thing to test.

Quote:

---

Sub-population analyses further showed greater efficacy demonstrated in patients who had a baseline IGA score of 3 (“moderate”) as compared to those with a baseline score of 2 (“mild”). Some of these patients even experienced a 3-point reduction in their IGA score, going from “moderate” to “clear.” This suggests Prurisol may be more effective in treating moderate to severe psoriasis patients to a greater degree than those patients who exhibit less severe symptoms. In moderate to severe psoriasis studies, the placebo response also tends to be lower.

---