Posted On: 03/18/2016 4:53:15 AM
Post# of 30066
Skin tissue engineering advances in severe burns: review and therapeutic applications
Received: 3 December 2015 Accepted: 11 January 2016 Published: 19 February 2016
Autologous dermo-epidermal composite skin substitutes
By far, the most promising autologous dermo-epidermal (composite) skin substitute reported is the cultured skin substitutes (CSS) developed in Cincinnati in the United States. This substitute is composed of collagen-glycosaminoglycan substrates which contains autologous fibroblasts and keratinocytes. Reported to be able to provide permanent replacement of both dermal and epidermal layers in a single grafting procedure [2, 79–83], this product was later commercialised as PermaDermTM [43]. PermaDermTM can currently be engineered within 30 days.
http://burnstrauma.biomedcentral.com/articles...016-0027-y
Received: 3 December 2015 Accepted: 11 January 2016 Published: 19 February 2016
Autologous dermo-epidermal composite skin substitutes
By far, the most promising autologous dermo-epidermal (composite) skin substitute reported is the cultured skin substitutes (CSS) developed in Cincinnati in the United States. This substitute is composed of collagen-glycosaminoglycan substrates which contains autologous fibroblasts and keratinocytes. Reported to be able to provide permanent replacement of both dermal and epidermal layers in a single grafting procedure [2, 79–83], this product was later commercialised as PermaDermTM [43]. PermaDermTM can currently be engineered within 30 days.
http://burnstrauma.biomedcentral.com/articles...016-0027-y
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