Posted On: 01/22/2016 12:52:05 PM
Post# of 72447
I'm more amazed by the human data, considering the subject was dosed at 30 mg/m2 and showed stable disease for 3+ months. Imagine the tumor killing effect of dosing at 750 mg/m2 multiple times weekly!
Quote:
AMAZING data, read this: In vivo efficacy of Kevetrin in the pancreatic MIA PaCa-2 xenograft model showed that tumor volumes were significantly reduced by 82% during 3 weeks of dosing at 200mg/kg. In a separate experiment when Kevetrin alone was dosed at 150mg/kg the tumor volume was reduced by 54%. The combination of Kevetrin and irinotecan further reduced tumor volumes by 88% showing synergistic activity.


