Posted On: 12/17/2015 12:09:35 PM
Post# of 72446
Some exerpts
"In an experiment using ovarian cancer cells removed from 16 patients, DBP testing was used to predict which tumors would respond to carboplatin, a standard chemotherapy drug. Patients whose cells responded strongly in the laboratory experienced significantly longer delays before their disease progressed."
"Going forward, the Dana-Farber investigators plan to test the predictive power of DBP technique on samples from patients entering clinical trials and monitor if their outcomes correlate with the test results"
"The technique is called Dynamic BH3 Profiling, or DBP. It is designed to detect the earliest signs that a cancer cell treated with a drug is beginning to destroy itself through apoptosis, a natural quality-control process that rids the body of unneeded or dangerously abnormal cells."
"The death process may take several days, but with the DBP test, scientists can identify which drug or drug combination has most effectively jump-started pro-death signaling.
"http://m.medicalxpress.com/news/2015-02-precision-medicine-tool-personalize-cancer.html
"In an experiment using ovarian cancer cells removed from 16 patients, DBP testing was used to predict which tumors would respond to carboplatin, a standard chemotherapy drug. Patients whose cells responded strongly in the laboratory experienced significantly longer delays before their disease progressed."
"Going forward, the Dana-Farber investigators plan to test the predictive power of DBP technique on samples from patients entering clinical trials and monitor if their outcomes correlate with the test results"
"The technique is called Dynamic BH3 Profiling, or DBP. It is designed to detect the earliest signs that a cancer cell treated with a drug is beginning to destroy itself through apoptosis, a natural quality-control process that rids the body of unneeded or dangerously abnormal cells."
"The death process may take several days, but with the DBP test, scientists can identify which drug or drug combination has most effectively jump-started pro-death signaling.
"http://m.medicalxpress.com/news/2015-02-precision-medicine-tool-personalize-cancer.html
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