Null p53 is another way of saying mutant p53. A null allele is a mutant copy of the p53 gene. As a result, the expressed proteins completely lack their normal functions. One of Kevetrin’s MOA is degradation of mutant p53s.

I’m not surprised that new aliases (bashers) started to appear after the article. The only way to shut them up is with good hard facts. Hopefully Leo can provide us with the ammos soon.