Posted On: 07/03/2015 1:21:09 PM
Post# of 22465
Scientists use nanoparticles to shut down mechanism that drives cancer growth
In a major step toward developing a novel therapy that targets epithelial–mesenchymal transition, scientists from UCLA and City of Hope have become the first to inhibit the mechanism of Twist using nanoparticles to deliver a nucleic acid called small interfering RNA, or siRNA, into tumor cells. In mouse models, delivering siRNA into cancer cells inhibited the expression of Twist, which in turn reduced epithelial-mesenchymal transition and dramatically reduced the size of tumors.
http://www.nanowerk.com/nanotechnology-news/newsid=40673.php
In a major step toward developing a novel therapy that targets epithelial–mesenchymal transition, scientists from UCLA and City of Hope have become the first to inhibit the mechanism of Twist using nanoparticles to deliver a nucleic acid called small interfering RNA, or siRNA, into tumor cells. In mouse models, delivering siRNA into cancer cells inhibited the expression of Twist, which in turn reduced epithelial-mesenchymal transition and dramatically reduced the size of tumors.
http://www.nanowerk.com/nanotechnology-news/newsid=40673.php
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