Just like any start up biotech they struggled, they changed their name in the early 80's (sound familar) they they traded side ways for a long time until JnJ partnered on EPO which they gave them to much (not as bad S MNKD of course) but it got them jump started so they could bring Neupogen to market on their own (sound familar?). If you have done your homework and are satisfied, buy when you can and hold, not for a day not for a year but until they win or lose.... JMO of course... I bought this stock for MANF the rest are just steps, if MANF fails, my investment fails but that is the risk I am willing to take so I wont bash my bride nor the family because it just doesn't make sense. Dave will tell you its healthy but that is not true, if you called your wife a whore when things didn't go your way eventually the relationtionship will fall apart, not what I would want to do with my money.... I know everyone wants to yell out Kool and the gang but we have some serious invertors aboard here and we are all very focused on this company and came to this board to share our positive thoughts not bash the company nor its employees! GLTU in the future and I hope this works out for all but keep in mind, nothing is a guarntee.....