Joseph Rubinfeld Phd. has publically announced AMBS affiliation and Dr. Urano is now publically identifying MANF as a key component in the battle for a cure of Wolfram's disease. Two HUGE PR's today. It is difficult to overestimate the importance of having Rubinfeld come out publically and announce his support for AMBS. His connections in the BP and biotech domain are iconic, to say nothing of his familiarity with the structure and workings of the FDA. Like the man said, "we are there." Big year coming for AMBS!!