Prurisol is a small molecule, acting on the principles of immune modulation and PRINS reduction that has been found to be effective against psoriasis in animal models, both in induced psoriasis as well as a xenograft model with human psoriatic tissue.

Chemistry/PK

Prurisol is a small molecule with a molecular weight of less than 500 MW. It is synthesized through a five-step process using commercially available starting materials. It is 25% orally bioavailable allowing the potential for oral administration. Prurisol acts through immune modulation and PRINS reduction.

Patent Protection

A patent application covering Prurisol was filed in January of 2012.