Warp's irritation with our old friend on IHUB is understandable given his track record of abuse there. Many have chosen to leave because of it. Fortunately such behavior will not be tolerated here. Let's get back to the incredible DD that has been shared over the past year by many posters, and Warp is one of the best! These are exciting days for AMBS, with the commercial launch of LYPRO within months now, and the AZ conference in Copenhagen in July with announcements of LYMPROS acuity results, and a likely partnership announcement. Add into the mix that Dr. Urano is hard at work with MANF regarding Wolfram's disease and is actively seeking a Pharma partner. Gerald has stated that if the upcoming results of MANF studies regarding Wolfram's syndrome are compelling, a Wolframs orphan IND may be submitted as AMBS highest priority. How would that relate to RP's orphan IND? Not exactly sure, but there is a "whole lot of shaking going on!"