NICE!! This is amazing! This study demonstrates that Silencing of CD40 and CD80 doesn't just slow down rejection of heart or organ transplant, BUT CREATES a healthy tolerance of the new organ.

I like where this is going...I can see why more professionals might be getting on board here. Many moving parts to this growing company it seems.

Quote:

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At end of point of experiment, cardiac graft tissues were harvested, the pathological changes
in the allografts were examined (Figure 3B). The rejected hearts (Figure 3B-a), demonstrated
severe cellular and humoral rejection, indicated by lymphocyte infiltration, hemorrhage,
infarction and thrombosis. Opposed to the rejected mice, the grafts from the tolerant mice
treated with CD40 and CD80 siRNAs showed minimal pathological changes. There was no
cellular infiltration, infarction nor thrombosis (Figure 3B-b). These results show that CD40
and CD80 silencing can prevent induce cardiac allograft rejection and induce allograft
tolerance.

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Thank you for intercepting and sharing this NEW4THIS!