Neutrolis Shares Breakthrough Findings at Major Rheumatology Event

Neutrolis Inc. Makes Headlines with Late-Breaking Study
Neutrolis Inc. has recently made exciting strides in the realm of biopharmaceutical innovation, having its abstract selected for a podium presentation at an important rheumatology conference. The late-breaking findings highlight the efficacy of Neutrolis's groundbreaking exDNASE™ therapeutic platform, which is designed to tackle Neutrophil Extracellular Traps (NETs) — a key factor in numerous inflammatory disorders.
Key Presentation Highlights at ACR Convergence 2025
During the prestigious American College of Rheumatology (ACR) Convergence 2025, taking place in late October, the company will showcase early proof of concept data pertinent to patients suffering from systemic inflammatory disorders. Chief Executive Officer Anthony Aiudi emphasized the importance of this research, which focuses on DNASE1L3, a novel therapeutic agent aimed at effectively degrading and inactivating NETs.
Insights from the CEO
"We are excited to present data at ACR Convergence 2025 that validate DNASE1L3 as a novel therapeutic approach to degrade and inactivate NETs, a central driver of systemic inflammatory disorders," Aiudi remarked. These results not only represent a significant achievement for Neutrolis but also highlight the potential of developing a new class of disease-modifying therapies that could potentially administer rapid effects without the adverse impacts of traditional immunosuppressive treatments.
Details of the Oral Presentation
The presentation will provide insights into a unique fusion protein, NTR-441, which combines albumin with DNASE1L3 for the strategic and rapid enzymatic inactivation of NETs in subjects with DNASE1L3 deficiency. Dr. Toby Fox, Co-founder and Chief Scientific Officer of Neutrolis, will lead the presentation, underscoring the innovative research methodologies the company employs.
Schedule for ACR Convergence 2025
Attendees interested in these findings can mark their calendars: the oral presentation is scheduled for October 29, 2025, from 8:45 AM to 9:00 AM CT. It is part of the Late-Breaking Abstracts session, specifically within sessions LB19–LB24.
Understanding Neutrolis's Mission
Neutrolis Inc. is carving a niche in the clinical-stage biotech landscape with its innovative approach to treating chronic inflammatory diseases. Unlike traditional methods that often lead to broad immunosuppression, the company's therapies specifically target and dismantle harmful NETs, which are known to lead to tissue damage and persistent inflammation, thereby providing patients a much-needed alternative treatment avenue.
A Transformative Approach to Medicine
This next-generation therapeutic strategy aims to restore immune balance by directly addressing the upstream causes of diseases like lupus and rheumatoid arthritis. Neutrolis's focused efforts intend to fill the gaps left by existing therapies, particularly in areas where patients continue to experience flare-ups and inadequate responses to treatment. They strive to bring transformative solutions that not only manage symptoms but also modify the disease course.
Learn More About Neutrolis
The company’s website offers a wealth of information regarding ongoing projects and therapeutic insights. Interested parties and investors can discover more about Neutrolis's commitment to revolutionizing treatment options for various autoimmune disorders, as well as opportunities for collaboration and inquiry.
Frequently Asked Questions
What is the main focus of Neutrolis Inc.?
Neutrolis Inc. focuses on developing innovative therapies aimed at degrading Neutrophil Extracellular Traps (NETs) to treat inflammatory disorders effectively.
When will Neutrolis present their findings?
The presentation will take place on October 29, from 8:45 AM to 9:00 AM CT at the ACR Convergence 2025.
Who is leading the presentation at ACR?
Dr. Toby Fox, Co-founder and Chief Scientific Officer of Neutrolis, will lead the presentation.
What is the significance of DNASE1L3?
DNASE1L3 is a novel therapeutic agent designed to degrade and inactivate harmful NETs, central to many systemic inflammatory disorders.
Where can I find more information about Neutrolis?
Additional information can be found on Neutrolis's official website, where they discuss their research and developments in more detail.
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