Neurocrine Biosciences Shows INGREZZA's Effectiveness in TD Relief
Neurocrine Biosciences Highlights INGREZZA Efficacy in Tardive Dyskinesia
Neurocrine Biosciences, Inc. (NASDAQ: NBIX) has recently shared compelling data regarding its treatment, INGREZZA (valbenazine) capsules, emphasizing its positive impact on individuals living with tardive dyskinesia (TD). These findings provide evidence surrounding the role of INGREZZA in improving functional outcomes and overall health-related quality of life for patients suffering from this challenging condition.
Study Overview and Findings
Recent Presentations
New analyses from a Phase 4 randomized withdrawal study illustrate that patients who continued their treatment with INGREZZA reported notable improvements in their daily functioning and health status. The results were recently presented at a prominent pharmacoeconomics conference, spotlighting the necessity of ongoing research into effective treatments for tardive dyskinesia.
Patient Experiences
Understanding how tardive dyskinesia disrupts normal life, Dr. Eiry W. Roberts, Chief Medical Officer at Neurocrine Biosciences, expressed concern over the constraints that the disorder can impose. “Patients often experience pain and anxiety, affecting their ability to engage in work and personal interactions.” The data support the argument that continued treatment with INGREZZA can address these critical elements of a patient’s life.
Improvements in Quality of Life
Positive Health-Related Quality of Life Outcomes
In the study, 127 patients receiving up to 80 mg of INGREZZA for eight weeks displayed encouraging results in areas such as mobility, self-care, usual activities, and anxiety/depression. Patients continuing on INGREZZA for an additional eight weeks reported sustained improvements, particularly in mobility and reductions in anxiety.
Functional Outcomes
Results highlighted in the study indicate that patients demonstrated improved functioning in work and social dynamics, attributable to ongoing treatment with INGREZZA. The data showed meaningful reductions in scores for various aspects of life, enhancing a patient’s capability to engage in everyday activities.
Comprehensive Analysis and Impact on Treatment
Broader Research Context
This data contributes significantly to the existing body of evidence regarding tardive dyskinesia treatments, affirming INGREZZA's place in a robust therapeutic landscape. The ongoing evaluation of treatment effectiveness resonates with healthcare providers and patients alike, marking a vital step in managing tardive dyskinesia symptoms.
Studying Patient Dosing Patterns
Additional research being presented at the conference includes analyses of real-world dosing patterns for vesicular monoamine transporter-2 inhibitors, highlighting variations in treatment approaches among patients with tardive dyskinesia.
About Tardive Dyskinesia
Tardive dyskinesia is a complex movement disorder that can manifest as uncontrollable movements, significantly impacting a person's quality of life. It is often linked to certain mental health medications, particularly antipsychotics, prompting a need for effective treatment options.
About Neurocrine Biosciences
Neurocrine Biosciences is committed to advancing treatment solutions for individuals grappling with under-addressed neurological conditions. With a diverse portfolio of FDA-approved therapies, including those for tardive dyskinesia and Huntington's disease, Neurocrine Biosciences utilizes its expertise to develop innovative treatments that prioritize patient welfare.
Frequently Asked Questions
What is INGREZZA used for?
INGREZZA is prescribed to treat tardive dyskinesia and chorea associated with Huntington's disease, providing relief from involuntary movements.
How does INGREZZA work?
INGREZZA works by selectively inhibiting vesicular monoamine transporter 2 (VMAT2), which helps to modulate dopamine levels in the brain, reducing involuntary movements.
What improvements can patients expect?
Patients may experience significant reductions in symptoms, enhanced mobility, better self-care capabilities, and an overall improved quality of life.
Is there any risk associated with INGREZZA?
While INGREZZA is effective for many patients, it can cause side effects, and patients are advised to consult with their healthcare provider regarding any concerns.
How can patients participate in studies about INGREZZA?
Patients interested in participating in ongoing or future studies can talk with their doctors or reach out to Neurocrine Biosciences directly for potential opportunities.
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