MetaVia's Exciting Developments at MASH-TAG Conference 2025

MetaVia Announces Advisory Committee Meeting at MASH-TAG Conference

MetaVia Inc. (NASDAQ: MTVA), a pioneering clinical-stage biotechnology firm dedicated to revolutionizing treatment options for cardiometabolic diseases, is thrilled to hold an Advisory Committee session during the 9th Annual MASH-TAG Conference. This prestigious event provides an excellent platform to share insights regarding their promising top-line results from a significant Phase 2a clinical trial of DA-1241, a groundbreaking G-Protein-Coupled Receptor 119 (GPR119) agonist.

Significant Clinical Findings of DA-1241

The focus of the Advisory Committee meeting is on the encouraging 16-week outcomes observed in the two-part clinical trial featuring DA-1241, specifically targeting patients experiencing metabolic dysfunction-associated steatohepatitis, commonly referred to as MASH. The meeting at the MASH-TAG Conference, taking place from January 9-11, brings together industry experts and stakeholders to discuss the implications of these results, held at the Chateaux Deer Valley venue.

Meet the Team and Discuss Research Outcomes

MetaVia's management and clinical team are eagerly awaiting your visit at the Exhibit Hall during the MASH-TAG Conference. Attendees will have the unique opportunity to engage with them, gaining valuable insights regarding the innovative clinical trial results of DA-1241. This interaction enhances understanding and promotes collaboration across the field.

Overview of MetaVia's Research and Development

MetaVia Inc. is at the forefront of clinical biotechnology, with an unwavering focus on transforming the landscape for treating cardiometabolic conditions. Their current developmental pipeline includes DA-1726, which targets obesity, alongside DA-1241, which aims to combat Metabolic Dysfunction-Associated Steatohepatitis (MASH). What sets DA-1726 apart is its dual agonistic capability on glucagon-like peptide-1 receptors (GLP1R) and glucagon receptors (GCGR).

The Impact of Novel Therapeutics

The innovative design of DA-1726, a novel oxyntomodulin (OXM) analogue, positions it as a pioneering candidate that could surpass traditional GLP1R agonists by enhancing energy expenditure while reducing food intake. Meanwhile, DA-1241 promotes the production of essential gut peptides such as GLP-1, GIP, and PYY—critical players in regulating appetite and metabolic health. The results from prior pre-clinical studies have illuminated DA-1241's potential, indicating benefits in liver inflammation and overall glucose control.

Company Mission and Vision

MetaVia is devoted to addressing the urgent health challenges posed by cardiometabolic diseases. Their mission encompasses not only the development of novel therapeutic agents but also the commitment to understanding the underlying pathophysiology. This understanding is essential for crafting effective treatment solutions that can lead to substantial improvements in patient outcomes.

Future Directions and Research Goals

As MetaVia continues to advance its clinical programs, the data emerging from the ongoing studies will play a pivotal role in shaping future therapeutic strategies. Their relentless pursuit of excellence in researching and developing innovative treatments reflects a commitment to enhancing patient care within cardiometabolic health.

Frequently Asked Questions

What is the purpose of the Advisory Committee meeting at MASH-TAG 2025?

The meeting aims to discuss the encouraging results from the Phase 2a clinical trial of DA-1241, focusing on its effectiveness in treating metabolic dysfunction.

What does DA-1241 target?

DA-1241 is designed to address metabolic dysfunction-associated steatohepatitis (MASH) by acting as a GPR119 agonist, aiming to improve liver health and metabolic outcomes.

Who can participate in discussions during the conference?

Industry stakeholders, healthcare professionals, and attendees of the MASH-TAG Conference are encouraged to engage with MetaVia's team in the Exhibit Hall to discuss the trial results.

What are the innovative features of DA-1726?

DA-1726 is a unique oxyntomodulin analogue, functioning as a dual agonist that impacts both GLP1R and GCGR, aiming to achieve enhanced weight loss compared to traditional therapies.

How can I find out more about MetaVia’s research?

For more information on MetaVia's work and updates on its pipeline, visiting their official website will provide insights into their projects and future directions.

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