Collaboration Between Azenta and Form Bio to Transform Gene Therapy
Strategic Partnership for AAV Gene Therapy Advancement
In a significant push towards revolutionizing gene therapy, Azenta, Inc. (Nasdaq: AZTA) has partnered with Form Bio to enhance the development of adeno-associated virus (AAV) gene therapies. This collaboration aims to streamline the entire process of gene therapy development, ultimately providing safer and more effective therapies to patients in need. By integrating cutting-edge technology with robust sequencing capabilities, this partnership seeks to reduce both time and costs associated with bringing lead candidates to market.
A Comprehensive Integrated Solution
At the heart of this partnership lies a fully integrated sequencing and data analysis solution designed to enhance AAV gene therapy development. GENEWIZ, a subsidiary of Azenta Life Sciences, will utilize its top-tier next-generation sequencing services alongside Form Bio's innovative AI and machine learning-driven analysis. Together, these services offer invaluable insights into AAV capsid contents, significantly boosting the safety, efficacy, and manufacturability of gene therapies.
Breaking Ground in Gene Therapy Workflows
GENEWIZ will take charge of synthesizing and packaging transgene expression cassettes while delivering high-quality, long-read sequencing services tailored for AAV gene therapies. Form Bio will contribute by conducting in-depth AAV Genome Integrity Characterization, utilizing their Long-read AAV Analysis (LAAVA) software to pinpoint opportunities that enhance vector integrity and safety. The combination of these strengths is poised to facilitate a seamless workflow, enhancing vector design and development efficiency.
What This Means for Researchers
The collaboration has garnered attention, particularly for its potential to transform traditional workflows in gene therapy development. Ginger Zhou, President at GENEWIZ, expressed enthusiasm about the partnership, stating, "Our collaboration with Form Bio marks a major step forward in simplifying AAV gene therapy workflows." This collaboration is set to enable researchers to make data-driven decisions that foster breakthroughs in gene therapy.
Accelerating Timelines and Enhancing Safety
Andrew Busey, Co-Founder and CEO at Form Bio, highlighted the importance of integrating their genome integrity insights directly into sequencing workflows. This approach will not only accelerate development timelines but also enhance vector safety and improve the clinical success rates of new therapies.
Upcoming Launch and Presentation
The partnership's official launch is anticipated during a prominent industry event: the 27th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT). Both Azenta and Form Bio will exhibit their innovative collaborative work and present a poster titled "The Long and Short of It: Comparing Next Generation Sequencing Methods for Quality Control in AAV Development". This presentation, scheduled for a specific date in May 2025, promises to showcase the tangible impacts of their collaboration.
About Form Bio
Form Bio is at the forefront of AI and computational solutions, focusing its efforts on driving therapeutic development within cell and gene therapy. Their proprietary FORMsightAI platform is instrumental in facilitating rapid genome integrity characterization, thereby accelerating the selection of viable lead candidates. Through combining AI-driven design with deep expertise spanning molecular biology and data science, Form Bio is reshaping therapeutic development by enhancing safety and efficacy while streamlining the process.
About Azenta Life Sciences
Azenta, Inc. (Nasdaq: AZTA) is a premier provider of comprehensive life sciences solutions. With a commitment to bringing breakthroughs to market quicker, Azenta offers an impressive array of cold-chain sample management solutions and multiomics services vital for drug development and clinical research. The company's reliable products and services support top-tier pharmaceutical and biotech companies, fortifying their presence globally.
Frequently Asked Questions
What is the focus of Azenta's partnership with Form Bio?
The partnership is centered on enhancing the development of AAV gene therapies by integrating advanced sequencing and AI-driven analysis solutions.
How will this collaboration benefit researchers?
Researchers will gain access to improved insights and workflows that will help accelerate the development of gene therapies while enhancing safety and efficacy.
What technology does Form Bio provide?
Form Bio offers AI and computational solutions, particularly through their FORMsightAI platform, which aids in genome integrity characterization for nucleic acid-based therapies.
When is the partnership set to officially launch?
The partnership will officially debut at the 27th Annual Meeting of the American Society of Gene & Cell Therapy in May 2025.
What is Azenta’s role in this collaboration?
Azenta will leverage GENEWIZ's sequencing expertise to streamline the workflows surrounding AAV gene therapy development.
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