BridgeBio Pharma Highlights ATTRibute-CM Data at 2025 ESC Congress
Overview of BridgeBio Pharma's Contribution at ESC Congress 2025
BridgeBio Pharma, Inc. (NASDAQ: BBIO), a pioneering biopharmaceutical company dedicated to advancing treatment solutions for genetic diseases, is scheduled to make a significant impact at the upcoming European Society of Cardiology (ESC) Congress 2025. This prestigious event will be noted for showcasing new research developments and innovative therapeutic options, and BridgeBio will take center stage with multiple presentations centered on their groundbreaking ATTRibute-CM study.
Key Presentations During the ESC Congress 2025
Rapid-Fire Oral Presentation
Among the highlights for BridgeBio is a rapid-fire oral presentation that will provide exciting insights into the open-label extension data from the ATTRibute-CM study. This presentation will illustrate several critical findings, including the effects of Acoramidis on cardiovascular mortality rates at the 42-month mark, discussed by leading expert Kevin Alexander, M.D., from Stanford University School of Medicine.
ePosters on Innovative Findings
In addition to the oral presentation, two ePosters will delve into pertinent topics that emerged during the ATTRibute-CM study. Nitasha Sarswat, M.D. from UChicago Medicine, will present findings regarding the impact of Acoramidis on NT-proBNP levels at Month 30. This data aims to better understand how Acoramidis may contribute to improved cardiac health outcomes compared to placebo treatments.
Furthermore, Julian Gillmore, M.D., Ph.D., from University College London, will highlight the results indicating a beneficial effect of Acoramidis on patients with ATTR-CM, measuring changes from baseline in NAC ATTR Stage at Month 30. These well-structured studies offer a comprehensive view of Acoramidis' effectiveness.
Understanding Acoramidis and Its Implications
Acoramidis, marketed as Attruby™, is a transthyretin stabilizer developed for the treatment of cardiac amyloidosis (ATTR-CM). Its clinical goal is to reduce cardiovascular death and related hospitalizations in adults. The promising data surrounding Acoramidis underscores its potential in managing this challenging condition.
Safety Profile of Attruby™
As with any treatment, understanding the safety profile is crucial. Noteworthy adverse reactions associated with Attruby include diarrhea, which occurs at a rate of 11.6% compared to 7.6% in placebo, and upper abdominal pain occurring in 5.5% of patients. Fortunately, most side effects reported in clinical trials were mild and manageable, with discontinuation rates similar to those of placebo group participants.
BridgeBio's Commitment to Genetic Medicine
Founded in 2015, BridgeBio Pharma is on the forefront of biopharmaceutical innovation, striving to deliver transformative medicines for genetic diseases. The company’s mission is rooted in applying cutting-edge science to develop treatments that can significantly improve the lives of patients. The team's extensive expertise in drug discovery and development embodies their commitment to advancing genetic therapies promptly.
Staying Informed about BridgeBio
To stay updated on their latest developments, individuals can visit BridgeBio's official website and follow them across various social media platforms like LinkedIn, Twitter, and Facebook. Keeping abreast of their research achievements can provide deeper insights into how they are shaping the future of medicine.
Contact Information
For media inquiries or to gain further insights into BridgeBio's advancements, you may reach out to their media contact, Bubba Murarka, Executive Vice President, Corporate Development, at contact@bridgebio.com or call (650)-789-8220. Additionally, their investor relations contact, Chinmay Shukla, Senior Vice President, Strategic Finance, can be reached at ir@bridgebio.com.
Frequently Asked Questions
What is the significance of the ATTRibute-CM study?
The study evaluates the efficacy and safety of Acoramidis in treating patients with ATTR-CM, focusing on critical health outcomes such as cardiovascular mortality.
Who will present the data at the ESC Congress?
The data will be presented by notable professionals, including Kevin Alexander, M.D., and Nitasha Sarswat, M.D., among others.
What is Acoramidis, and how does it work?
Acoramidis is a transthyretin stabilizer aimed at treating the cardiomyopathy associated with transthyretin-mediated amyloidosis, helping to stabilize proteins and reduce symptoms.
What adverse reactions are linked to Acoramidis?
Common reactions include diarrhea and upper abdominal pain; however, they typically resolve without treatment discontinuation.
How can I learn more about BridgeBio Pharma?
Visit their official website or follow them on LinkedIn, Twitter, and Facebook for the latest news and updates on their projects and findings.
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