Arctic Therapeutics Secures Major Funding for Dementia Research

Arctic Therapeutics Secures Major Funding

Arctic Therapeutics, a pioneering Icelandic drug discovery and development company, has successfully closed a significant €26.5 million oversubscribed Series A financing round. This funding marks an important step in their mission to develop innovative treatments for dementia and skin diseases.

Funding Purpose and Goals

The proceeds from this investment will aid in accelerating Arctic Therapeutics' research focused on anti-amyloid treatments. Their initiatives aim to address rare and common forms of dementia, providing new options for patients navigating these challenging conditions. Additionally, the company is set to launch a new class of therapies targeting inflammatory skin diseases, which is a crucial area of unmet medical need.

Key Investors Involved

The financing comes from a diverse group of international investors, including the EIC Fund and Iceland's leading investment firm, Kaldbakur. Notably, the Sanos Group and Swiss-based Cerebrum DAO are also part of the syndicate, along with the Lurie Family Foundation.

Innovative Clinical Approaches

Arctic Therapeutics will utilize this funding to push their frontrunners, AT-001 and AT-004, further into clinical trials. Notably, the European Medicines Agency has approved a pivotal phase IIb/III clinical trial for AT-001, which is designed to combat Hereditary Cystatin C Amyloid Angiopathy - a rare form of familial dementia. With the new funding, ATx plans to broaden the evaluation of AT-001 into other dementia types, including Alzheimer's disease.

Importance of Amyloid Research

Recent findings underline the significance of amyloid proteins in dementia. The therapies developed by Arctic Therapeutics focus on preventing the aggregation of these harmful proteins, which can lead to severe cognitive decline. Co-founder and CEO, Ivar Hakonarson, emphasized that this funding represents a critical milestone in their journey to address the unmet medical needs associated with these diseases.

Plans for Skin Disease Treatments

In tandem with their neurological efforts, Arctic Therapeutics is gearing up to initiate a phase IIa clinical trial for AT-004, targeting acne vulgaris first. This approach is particularly exciting as it opens avenues for additional treatments for related inflammatory skin conditions such as atopic dermatitis, rosacea, and psoriasis.

Strategic Board Appointment

To bolster their strategic direction, Arctic Therapeutics appointed Jeppe Ragnar Andersen, CEO of Sanos Group, to their board of directors. His expertise in dermatology and clinical studies in Alzheimer’s further aligns with the company's therapeutic focus. Andersen expressed enthusiasm for collaborating with the ATx team to develop groundbreaking treatments for both dementia and skin disorders.

A Recognition of Potential

Being selected for the prestigious EIC Scaling Club last year further highlights Arctic Therapeutics' potential. This exclusive community aims to scale promising companies into unicorns and aligns with the EIC Fund's objective to invest in companies capable of addressing significant global challenges.

Addressing Global Health Needs

According to Svetoslava Georgieva, Chair of the EIC Fund Board, investing in innovative solutions to combat the global healthcare challenge presented by dementia not only represents a responsibility but also a tremendous opportunity. With dementia affecting millions in Europe, the need for effective preventive treatments is more urgent than ever, and Arctic Therapeutics is poised to make a substantial impact in this space.

About Arctic Therapeutics

Established as a spin-off from the US-based Center for Applied Genomics, Arctic Therapeutics aims to utilize applied genomics to create safer and more effective treatments for severe diseases. With operations not only in Iceland but also in the US and various collaborations across Europe, they are dedicated to transforming drug development in impactful ways.

Frequently Asked Questions

What is the main focus of Arctic Therapeutics?

Arctic Therapeutics focuses on drug discovery and development for conditions such as dementia and inflammatory skin diseases.

How much funding did Arctic Therapeutics secure?

The company secured €26.5 million through an oversubscribed Series A financing round.

Who are the key investors in this financing round?

The financing was led by a diverse group of international investors, including the EIC Fund and Kaldbakur.

What are AT-001 and AT-004?

AT-001 is an oral treatment for preventing harmful amyloid protein aggregation, while AT-004 aims to treat acne vulgaris and other skin conditions.

What is the EIC Scaling Club?

The EIC Scaling Club is a prestigious community for promising scaleups aimed at helping them scale into unicorns and tackle significant global challenges.

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