Lexogen's Groundbreaking Project in RNA Sequencing
Lexogen, a pioneering biotech company based in Vienna, has recently completed a remarkable data generation project alongside Ochre Bio. This collaboration produced extensive functional genomics datasets derived from primary human hepatocytes. With an impressive volume of over 120,000 samples, this project marks a significant milestone in the field of RNA transcriptomics.
About the Collaboration with Ochre Bio
Ochre Bio specializes in creating RNA medicines aimed at addressing under-treated chronic liver diseases. The company utilizes comprehensive human liver data, including proprietary gene perturbation and disease atlases, to facilitate the discovery of new targets for therapeutic development. Their innovative OBELiX software plays a crucial role in analyzing gene biology within human cells and tissues, enhancing the efficiency of target prioritization through AI-driven insights.
Importance of High-Fidelity RNA-Seq Data
The high-fidelity RNA-Seq data produced through this partnership forms the backbone of Ochre's human discovery platform. Lexogen's NGS Services has established itself as a trusted long-term sequencing collaborator with Ochre Bio, providing superior RNA-Seq data from diverse sample types, including bio-banked FFPE, microorgan, and primary hepatocyte samples. Their adherence to cGLP standards and use of proprietary technologies developed under stringent ISO 13485 regulations ensures that the data generated is of the highest quality.
Lexogen’s Commitment to Quality and Consistency
With a solid commitment to quality and consistency throughout their processes, Lexogen focuses on delivering reliable data for their clients and industry partners. The team at Lexogen is dedicated to supporting advancements in research and innovation aimed at improving patient outcomes. Their proprietary THOR and pooling technologies allow for extraction-free RNA-Seq, which contributes to consistency and high resolution while managing projects at scale.
Expert Insights on Data Quality
Quin Wills, Founder and CEO of Ochre Bio states, "In AI-driven target discovery, a platform is only as powerful as the data fueling it. With over 120,000 samples derived from primary human hepatocytes, obtaining rigorous data quality is fundamental for meaningful results. High-fidelity sequencing data enables machine-learning models to effectively distinguish biological signals from technical noises." This statement underscores the necessity of having dependable data to facilitate accurate interpretations in complex biological settings.
Stephane Barges, CEO of Lexogen, expressed the company's dedication to their mission, stating that their goal is to deliver accurate services at scale. "We aim to assist our partners in their discoveries and accelerate innovation in healthcare, influencing the development of therapeutic and diagnostic tools aimed at enhancing patient lives," he says.
About Lexogen
Lexogen boasts two decades of experience in the realm of transcriptome analysis and RNA sequencing. They provide a suite of solutions including kits, reagents, and bioinformatics services, all manufactured in Vienna, Austria. Lexogen prides itself on being ISO 9001 and 13485 certified, ensuring that their offerings adhere to the highest industry standards, including compliance with cGLP and GDPR.
For those looking to explore more, more information is available about Lexogen and their services on their official website, ensuring that users can stay updated on their latest innovations and offerings.
Contact:
Email: [email protected]
Tel.: +43 1 345 1212
Frequently Asked Questions
What is the purpose of the collaboration between Lexogen and Ochre Bio?
The collaboration aims to generate comprehensive functional genomics datasets from primary human hepatocytes to aid in the development of RNA medicines for chronic liver diseases.
How many samples were involved in the Lexogen and Ochre project?
More than 120,000 samples were assessed during this large-scale data generation project.
What technologies does Lexogen utilize for RNA sequencing?
Lexogen employs proprietary extraction-free methods and high-resolution gene expression profiling platforms, including their THOR technology to maximize data quality.
What is the significance of high-fidelity RNA-Seq data for Ochre Bio?
High-fidelity RNA-Seq data is essential for achieving accurate AI-driven target discovery, ensuring data quality and reliability for therapeutic development.
How long has Lexogen been in operation?
Lexogen has been providing advanced solutions for transcriptome analysis and RNA sequencing for nearly 20 years.
