Transforming Liquid Biopsy Workflows with nRichDX and Hamilton
In an impressive collaboration, nRichDX has partnered with Hamilton to revolutionize the field of liquid biopsy sampling. With the integration of the nRichDX Revolution Plus™ Sample Prep System and Hamilton's Microlab STAR platform, this solution offers automated workflows that cater to high-yield extraction of precious biomolecules like cfDNA, cfRNA, cfTNA, and CTCs. The resulting system is validated through extensive use in both research and clinical laboratory settings, marking a significant advancement for the industry.
Automated, Efficient, and Versatile Operations
This ground-breaking technology introduces an end-to-end process for isolating various analytes from different biofluids such as plasma and urine, while minimizing the manual handling required. The collaboration between nRichDX and Hamilton allows laboratories to easily scale their operations. This flexibility is enhanced by the ability to process sample volumes ranging from just 1 mL to a substantial 100 mL in one go, catering to a broad array of research needs.
The Key Benefits of the Integrated Solution
Among the numerous advantages of this cutting-edge solution are:
1. Scalable Liquid Biopsy Workflows
The sample preparation process is fully automated, providing labs with a scalable solution that can adapt to various project sizes.
2. High-Yield Recovery
The partnership ensures consistent and high recovery rates of rare analytes from multiple types of biofluids, enhancing the reliability of test results.
3. Flexibility in Sample Sizes
Laboratories gain the ability to process a wide range of input volumes. This flexibility streamlines workflows and allows for tailored sample preparations based on individual resources.
4. Walk-Away Operation
The system supports extended hands-off operation, making it suitable for both research and clinical laboratory settings.
William Curtis, CEO of nRichDX, remarks, "We are setting a new benchmark for liquid biopsy sample preparation with this performance. Our collaboration with Hamilton significantly enhances the potential of laboratories to maximize analyte yields through scalable automation." Michael Mouradian, Vice President at Hamilton, adds, "This partnership exemplifies our commitment to the evolution of precision medicine. By integrating both technologies, we are facilitating reproducible liquid biopsy workflows that are flexible enough to meet varying laboratory demands."
Highlighting Achievements at AMP 2025
The significance of the nRichDX and Hamilton collaboration was prominently displayed at AMP 2025. Various scientific presentations and posters were shared, showcasing the innovative automated workflows for liquid biopsy. These insights attracted considerable attention from both molecular diagnostics experts and clinical leaders who are eager to address yield limitations in rare-analyte extraction.
The response to their integrated solution indicates a strong foundation for further joint developments, upcoming customer pilots, and increasing commercial engagements. For additional information, laboratories are encouraged to reach out directly for more details on the capabilities of the nRichDX-Hamilton solution.
About nRichDX
nRichDX is renowned for its advanced solutions tailored for isolating cfDNA, cfRNA, cfTNA, and CTCs. Their patented Revolution Sample Prep System™ is designed explicitly for liquid biopsies, effectively extracting crucial analytes from various biofluids. As a pioneering platform, it can handle sample volumes from 1 mL to 100 mL, using the unique nRicher™ Cartridges to significantly enhance analyte recovery.
The system aids in overcoming important challenges in precision medicine, like incomplete results due to inadequate sample sizes. Further exploration of their offerings can be conducted at nrichdx.com.
About Hamilton
With over 75 years of experience, Hamilton Company stands out as a distinguished leader in life sciences, focusing on precision measurement devices and automated liquid handling systems. Its headquarters in Reno, featuring key R&D affiliates in various global locations, enables Hamilton to cater to the worldwide scientific community effectively.
Hamilton leverages their expertise across several sectors, including liquid handling and automated storage solutions, to provide the essential tools necessary for pioneering scientific research. Their commitment to high-quality materials and exceptional craftsmanship guarantees performance and reliability, crucial for lab success.
Frequently Asked Questions
What does the nRichDX and Hamilton collaboration achieve?
The partnership enhances automated liquid biopsy sample preparation, enabling labs to achieve higher analyte yields and improved efficiency.
What are the key benefits of the integrated solution?
Key benefits include scalability, high-yield recovery, flexibility in sample sizes, and a walk-away operation, making it versatile for various laboratory settings.
Can different biofluids be processed?
Yes, the solution allows isolation from various biofluids such as plasma, urine, and others, ensuring broad applicability.
How does this technology enhance precision medicine?
By optimizing the extraction processes, it addresses challenges related to sample quality, thereby improving the reliability of test results in precision medicine.
Where can I find more information about nRichDX?
More detailed insights into their offerings and solutions can be found on their official website at nrichdx.com.
