Avacta Unveils New Clinical Findings on AVA6000 at ESMO Event

Author: Riley Hayes Updated: 09-08-2024 06:15 PM

Avacta Group plc Discusses Breakthrough AVA6000 Data

Avacta Group plc, a pioneering company in the life sciences sector known for its focus on innovative cancer treatments and diagnostics, is gearing up to present vital updates on its Phase 1a trial of AVA6000 at an upcoming esteemed medical event.

Event Highlights for AVA6000 Presentation

The presentation at the European Society for Medical Oncology (ESMO) Congress is scheduled in Barcelona and will feature significant findings derived from the trial involving AVA6000. This peptide drug conjugate, which is at the forefront of Avacta's research, integrates doxorubicin with a peptide specifically designed to be activated in the presence of Fibroblast Activation Protein (FAP) within the tumor microenvironment.

Details About the Trial and Presentation

The poster presentation will encompass updated data that highlights the progression of the Phase 1a trial, which is focused on patients suffering from FAP-positive solid tumors. The anticipation surrounding this session adds to the excitement within the oncology research community.

Key Presentation Information

The broader clinical context includes an array of details intended for practitioners and stakeholders alike. Here are the specifics of the presentation to note:

Title: A Phase I trial of AVA6000, a FAP-released, TME-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumours.
Session Title: Developmental therapeutics
Session Date and Time: Saturday, September 14, at 9 AM CEST
Location: Fira Barcelona Gran Via
Abstract Presentation Number: 646P
First Author: Professor Chris Twelves, University of Leeds

About Avacta Group plc and Its Innovations

Avacta Group plc is committed to redefining treatment possibilities in oncology through its innovative platforms. The company operates two primary divisions: Avacta Therapeutics, which is advancing clinical trials for highly targeted cancer drugs, and Avacta Diagnostics, focused on expanding diagnostic access and capabilities.

Advancements with the pre|CISION™ Platform

The leading program, AVA6000, represents a significant advancement in drug delivery and effectiveness, as it leverages the pre|CISION™ technology. This unique approach selectively targets FAP that is overexpressed in most solid tumors compared to normal tissue, thus minimizing systemic exposure while maximizing treatment efficacy.

With preliminary results indicating enhanced safety and a favorable tolerability profile in patients relative to conventional doxorubicin, the current studies aim to solidify AVA6000’s role in cancer treatment paradigms.

Contact Information for Inquiries

For further insights or inquiries regarding Avacta Group plc, please connect with the leadership team directly:

Avacta Group plc
Christina Coughlin, CEO
Michael Vinegrad, Group Communications Director
Tel: +44 (0) 1904 21 7070

Frequently Asked Questions

What is AVA6000?

AVA6000 is a peptide drug conjugate designed to release doxorubicin specifically in the tumor microenvironment, aimed at treating FAP-positive solid tumors.

What event will Avacta present at?

Avacta will present updated clinical trial data on AVA6000 at the ESMO Congress in Barcelona.

Who is the first author of the presented research?

Professor Chris Twelves from the University of Leeds is the first author of the research that will be presented.

What is the significance of the PAF in the oncology treatment of AVA6000?

FAP is a target selected for its upregulation in many solid tumors, allowing for more effective and selective treatment while sparing healthy tissues.

How can I learn more about Avacta's innovations?

For more information about Avacta Group plc and its groundbreaking work in cancer therapeutics, interested individuals should contact the company or visit their official website.

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