Revolutionizing Biopharma with AbZelectPRO™: A New Era in Cell Line Development
Introducing AbZelectPRO™: A Game-Changer for Biopharma
Abzena has made significant strides in the biopharmaceutical landscape with its innovative platform, AbZelectPRO™. This cutting-edge mammalian cell line development platform revolutionizes research cell bank timelines, enabling biopharma customers to achieve their goals in just 10 weeks. With the ability to produce up to 8g/L of high-quality titles prior to process development, AbZelectPRO™ stands as a beacon of efficiency and productivity.
Reducing Development Time and Costs
The brilliance of the AbZelectPRO™ platform lies in its integration of ProteoNic's 2G UNic® vector technology alongside Abzena’s established CHO host cell line. This powerful combination leads to a higher frequency of high-producing clones for both therapeutic proteins and recombinant vaccines. The result is a drastically reduced timeline, with significant improvements in protein production levels that positively impact the overall cost of goods for biopharma clients.
A Focus on Efficiency and Productivity
Simon Keen, the VP of Cell Line Development at Abzena, shares insights into the vision guiding this platform. "With AbZelectPRO™, our intention was to create a robust cell line development tool featuring shorter timelines, enhanced production levels, and cost reductions. The advancements achieved over the past months have been remarkable, and we are proud to present data that illustrates its practical benefits to our customers," Keen notes. This commitment reflects Abzena's dedication to providing solutions that fuel the progress of innovations in medical treatments.
Enhancing Protein Production Capabilities
The engineering behind the AbZelectPRO™ platform includes an optimized expression cassette specifically designed to cultivate stable clones that maintain their productivity over numerous generations. This feature has been beneficial for the production of challenging proteins, addressing complex tasks that often hinder development. The synergy between the 2G UNic® vector technology and Abzena’s methodologies significantly boosts expression levels, especially for bispecifics, fusion proteins, and other novel modalities.
Collaboration for Progress
Frank Pieper, CEO of ProteoNic, emphasizes the advantages yielded by their partnership: "Integrating our 2G UNic® technology with AbZelectPRO™ enhances its ability to improve output, particularly for challenging modalities. This collaboration allows biopharma companies to navigate high-yield scenarios efficiently." This teamwork encapsulates the essence of innovation in the biopharma sector, where partnerships pave the way for breakthroughs.
About Abzena
Abzena is recognized as a premier integrated CDMO; it specializes in bioconjugates and complex biologics. The company supports its clients from discovery through to commercial launch with tailored strategies designed to minimize risks while maximizing development speed. Abzena's versatile offerings include integrated programs and bespoke services that help biopharma innovators unlock their molecule's full potential and accelerate the delivery of new treatments to market. With state-of-the-art research, development, and cGMP facilities across various locations, Abzena stands at the forefront of biotech advancement.
About ProteoNic
ProteoNic is a forward-thinking biotechnology firm engaged in revolutionizing cell line generation and viral vector production. Dedicated to enhancing protein production yield and efficiency through its proprietary technologies, ProteoNic collaborates extensively within the biopharmaceutical industry, propelling innovative biologics, cell, and gene therapies. Their commitment to innovation signifies the promise of continued advancements in the field.
Frequently Asked Questions
What is AbZelectPRO™?
AbZelectPRO™ is Abzena's advanced mammalian cell line development platform designed to enhance productivity and reduce timelines in biopharma research.
How does AbZelectPRO™ improve production levels?
The platform integrates cutting-edge technologies to ensure higher producing clones and faster transitions from DNA to research cell banks.
Who collaborated with Abzena on this technology?
ProteoNic, with its proprietary 2G UNic® technology, partnered with Abzena to enhance protein production capabilities.
What benefits does the 2G UNic® vector technology offer?
This technology facilitates enhanced expression levels and productivity for challenging protein types such as bispecifics and fusion proteins.
What future developments can we expect from Abzena?
Abzena plans to continue innovating its platforms to improve biopharmaceutical processes and ensure faster delivery of new therapies to the market.
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