Nicox Collaborates with Glaukos on Innovative NCX 1728'
Nicox Partners with Glaukos on NCX 1728 Research
Nicox SA, an international ophthalmology organization, has recently entered into an exclusive collaboration with Glaukos Corporation. This partnership focuses on the research and global licensing of NCX 1728, a novel compound designed to address serious eye conditions such as glaucoma and various retinal diseases.
Key Features of the Agreement
The agreement allows Glaukos exclusive rights to license NCX 1728 globally. This includes upfront payments, milestone payment options, and potential royalties. This partnership aims to leverage Glaukos' expertise in ophthalmic disorder treatment and their innovative drug delivery systems to optimize NCX 1728 for several applications, including reducing intraocular pressure and providing neuroprotection.
Research Activities Funded by Glaukos
Under the terms, Glaukos will fully fund the preclinical research necessary to evaluate NCX 1728. The research is intended to explore the compound's effectiveness in the treatment of glaucoma and the potential for retinal disease applications. A Joint Steering Committee will manage this collaborative research program.
Strategic Development Focus
As part of this strategic alliance, Nicox will continue to concentrate on advancing its leading drug candidate, NCX 470, which is currently in Phase 3 development. NCX 470 is another NO-donating molecule aimed at lowering intraocular pressure for patients suffering from open-angle glaucoma and ocular hypertension.
About NCX 1728
NCX 1728 represents an innovative class of NO-donating phosphodiesterase-5 (PDE5) inhibitors. This unique formulation enhances and prolongs the effects of nitric oxide (NO), which is beneficial in treating various ocular conditions. The combination of NO donation and PDE5 inhibition can lead to improved therapeutic outcomes, particularly in situations requiring prolonged effects on intraocular pressure reduction.
About Nicox SA
Headquartered in Sophia Antipolis, France, Nicox SA is dedicated to developing cutting-edge solutions for vision preservation and ocular health enhancement. Their portfolio includes revenue-generating products such as VYZULTA®, exclusively licensed worldwide to Bausch + Lomb, and ZERVIATE®, licensed in multiple regions for treating allergic conjunctivitis.
Future Outlook
The collaboration between Nicox and Glaukos signifies a promising development not only for both companies but also for patients suffering from glaucoma and retinal diseases. With Glaukos handling the preclinical research, both parties will aim to optimize the therapeutic potential of NCX 1728, bringing innovative solutions to the ophthalmic market.
Frequently Asked Questions
What is NICX 1728?
NCX 1728 is a novel nitric oxide-donating phosphodiesterase-5 inhibitor aimed at treating glaucoma and retinal diseases.
How does the partnership benefit patients?
The collaboration aims to develop effective treatments that may significantly improve patients' conditions related to intraocular pressure and neuroprotection.
What role does Glaukos play in this agreement?
Glaukos will fund and conduct preclinical research for NCX 1728 and has the option to license the compound for global development.
What is the current status of Nicox’s development pipeline?
Nicox is currently focused on the Phase 3 development of NCX 470, its lead candidate for managing open-angle glaucoma.
Where can I find more information about Nicox?
More details about Nicox's products and developments can be found on their official website.
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