Molecular Partners Set to Present Groundbreaking Cancer Therapy
New Innovations in Cancer Treatment from Molecular Partners
Molecular Partners AG, a clinical-stage biotech firm, is making waves with its latest developments in targeted therapies for cancer. Among their promising candidates is MP0712, a Radio-DARPin therapeutic specifically designed to target DLL3 in small cell lung cancer (SCLC). In collaboration with Orano Med, they are pushing the boundaries in cancer treatment through innovative technology.
Understanding MP0712's Mechanism
Recent studies have demonstrated that MP0712 exhibits low kidney accumulation while achieving high uptake in tumor cells, indicating a targeted approach to combat cancer. The treatment has proven to inhibit tumor growth effectively in vivo, showing substantial promise in preclinical models. As a groundbreaking Radio-DARPin Therapeutic, MP0712 harnesses the power of a radioactive payload to deliver targeted therapy directly to cancer cells.
Upcoming Presentation at EANM 2024
This October, Molecular Partners will present their findings at the European Association of Nuclear Medicine (EANM) Congress. The presentation titled "Preclinical Assessment of Lead-212 (212Pb) Radio-DARPin Therapeutic (RDT) Targeting Delta-like Ligand 3 (DLL3) in Small Cell Lung Cancer (SCLC)" is part of the top-rated oral presentations at the congress. Scheduled for October 22, attendees can expect insightful data that underscores the effectiveness and safety profile of MP0712.
Details of the Presentation
Participants at EANM 2024 will have access to intricate details surrounding MP0712, including its biodistribution profile, which is crucial for determining its efficacy and safety. The presentation will occur during Session M2M Track, starting at 9:20 a.m. CET in Hall X1-X4, and aims to engage a global audience of oncology experts and professionals.
The Role of DLL3 in SCLC
Dll3 has established itself as a compelling target in the radiopharmaceutical space, mainly due to its overexpression in small cell lung cancer, with nearly 85% of cases showcasing high expression levels. This presents an opportunity for MP0712 to address a significant medical need, paving the way for tailored therapies that minimize damage to healthy tissues.
Transformative Potential of DARPin Therapeutics
The innovative approach of DARPin therapeutics offers a unique solution to complex challenges in drug design. These proteins are engineered to be highly specific and versatile, enabling simultaneous targeting of multiple pathways within cancer cells. With their robust pharmacological properties and stability, DARPins represent a significant advancement over traditional therapeutic modalities.
Building Collaborations for Success
Molecular Partners is not working alone in this endeavor. Their collaboration with Orano Med is a lighthouse showcasing how partnerships can accelerate innovation in drug development. With a focus on targeted alpha therapy, both companies are harnessing the unique properties of rare radioisotopes like lead-212 to enhance treatment outcomes for cancer patients.
Company Overview and Future Directions
Founded in 2004, Molecular Partners AG continues to pioneer the world of DARPin therapeutics, addressing various oncological challenges. Their commitment to clinical excellence is demonstrated through their various partnerships and in-house development programs aimed at delivering cutting-edge therapies. As they prepare to unveil their research at EANM 2024, the promise of new treatments on the horizon brings hope to many.
Contact Information
For more information about the company and its initiatives, interested parties can reach out to:
Seth Lewis, SVP Investor Relations & Strategy
Concord, Massachusetts, U.S.
Email: seth.lewis@molecularpartners.com
Tel: +1 781 420 2361
Laura Jeanbart, PhD, Head of Portfolio Management & Communications
Zurich-Schlieren, Switzerland
Email: laura.jeanbart@molecularpartners.com
Tel: +41 44 575 19 35
Frequently Asked Questions
What is MP0712?
MP0712 is a Radio-DARPin therapeutic targeting DLL3, specifically designed for the treatment of small cell lung cancer.
When will Molecular Partners present at EANM 2024?
The presentation is scheduled for October 22, 2024, at 9:20 a.m. CET.
How does MP0712 work?
MP0712 uses a targeted radioactive payload to selectively deliver therapy to cancer cells, minimizing damage to healthy tissue.
What is the significance of DLL3?
DLL3 is highly expressed in small cell lung cancer, making it a promising target for targeted therapies like MP0712.
Who should be contacted for more information?
Seth Lewis and Laura Jeanbart are contacts for further inquiries regarding Molecular Partners' research and initiatives.
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