Kuros Biosciences Marks Milestone with ASTRA Study Patient Enrollment

Kuros Biosciences Initiates a Groundbreaking Study for Bone Fusion

In an exciting development, Kuros Biosciences has taken a significant step forward by enrolling the first patient in its ASTRA (Ankle Subtalar arThrodesis Randomized Assessment) study. This global clinical trial aims to enhance foot and ankle fusion procedures, showcasing Kuros' commitment to advancing medical technology in surgical applications.

The ASTRA Study: Objectives and Methodology

The ASTRA study is a prospective, randomized, single-blinded clinical trial that focuses on the safety and performance of MagnetOs™ compared to traditional autograft methods. It involves multiple centers and seeks to recruit approximately 126 patients scheduled for hindfoot or ankle fusion surgeries. The trial will encompass various surgical techniques, including subtalar fusion.

Enrollment and Patient Expectations

Participants in the study will be randomized to receive either MagnetOs Putty or MagnetOs Easypack Putty, both used independently without mixing with other graft materials. The goal is to assess how these innovative products perform in promoting bone healing compared to patients' own bone grafts.

Importance of the Study in the Context of Orthopedic Surgery

As the demand for effective bone healing solutions continues to grow, the ASTRA study aligns perfectly with Kuros Biosciences' expanding strategy in the extremities market. By incorporating insights from previous successful trials like PROOF and PRECISE, Kuros aims to solidify the clinical evidence supporting MagnetOs in new anatomical regions like the foot and ankle.

The Role of Surgeons in Advancing Treatment

Dr. Jesse Doty, an orthopedic surgeon involved in the trial, expressed enthusiasm about the potential impacts of the study on patients facing complex hindfoot and ankle surgeries. With the limitations of autografts regarding availability and quality, this trial promises to present new solutions that could enhance surgical outcomes.

Significance of the Name ASTRA

The name ASTRA was thoughtfully chosen, deriving from the historical term for the talus bone, which showcases the study's focus on improving surgical outcomes in this critical area. By leveraging advanced biologic technologies, Kuros Biosciences aims to transform the landscape of surgical procedures and patient care.

Contact Information for Inquiries

For further details about the ASTRA study or general inquiries regarding Kuros Biosciences, interested parties can reach out to:

Alexandre Müller
Investor Relations
Tel: +41 43 268 32 31
IR@kurosbio.com

Daniel Geiger
Chief Financial Officer
Tel: +41 44 733 47 41
daniel.geiger@kurosbio.com

About Kuros Biosciences

Kuros Biosciences is recognized for its mission to innovate and develop biologic technologies. With operational bases in the United States, Switzerland, and the Netherlands, the company’s premier product is MagnetOs™, a cutting-edge bone graft used in various surgical procedures worldwide. As the demand for effective solutions in bone fusion proliferates, Kuros continues to explore and expand its product offerings for enhanced patient care.

Frequently Asked Questions

What is the ASTRA study about?

The ASTRA study is a clinical trial designed to assess the safety and performance of MagnetOs compared to autografts in foot and ankle fusion procedures.

How many patients will participate in the ASTRA study?

About 126 patients undergoing hindfoot or ankle fusions are expected to be enrolled in the study.

Who is leading the ASTRA study?

Dr. Jesse Doty is one of the principal investigators involved in the study, contributing to its execution and oversight.

What are MagnetOs?

MagnetOs are advanced bone graft materials developed by Kuros Biosciences, designed to enhance bone healing and fusion outcomes in surgeries.

How can I get more information about Kuros Biosciences?

More information can be obtained by contacting their investor relations team or visiting their official website.

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