Innovative Partnership Targets Cancer Drug Resistance with ENV105
Kairos Pharma Partners to Combat Cancer Drug Resistance
Kairos Pharma Ltd. (NYSE American: KAPA), a dynamic leader in the field of biopharmaceuticals, has taken a significant step in cancer treatment through its collaboration with PreCheck Health Services Inc. This pioneering partnership is designed to develop essential biomarkers aimed at enhancing the response of patients to ENV105, a promising therapy targeting resistant prostate and lung cancers.
Advancing Precision in Cancer Treatment
The focus of this innovative collaboration lies in the creation of companion biomarkers that will facilitate a more focused patient screening process. These biomarkers will help identify individuals who are likely to experience the greatest benefits from ENV105 during clinical trials. Utilizing advanced molecular diagnostics, this project aims to refine cancer care by ensuring that the most suitable patients are selected for therapy.
Key Clinical Trials
As part of this strategic initiative, Kairos Pharma and PreCheck will conduct robust analyses within two pivotal clinical trials. The first trial, targeting patients with EGFR-driven lung cancer (NCT05401110), seeks to identify biomarkers through somatic gene profiling prior to treatment. The second trial (NCT05534646) focuses on patients with castrate-resistant prostate cancer and is designed to validate existing biomarkers while discovering new ones linked to ENV105's efficacy.
Innovation through Technology
Employing PreCheck's cutting-edge SolidTumorCheck+ platform, the analysis of biopsy tissues and circulating tumor cells will play a critical role in this collaboration. This technology allows Kairos Pharma to not only analyze tissue samples but also consider non-invasive methods through liquid biopsies, offering new insights into patient responses while streamlining treatment processes.
The Role of Companion Diagnostics
Development of companion diagnostics is a core component of this collaboration. These FDA-approved tests aim to help identify patients who stand to gain the most from specific therapies. PreCheck plans to implement a three-gene PCR analysis, among other tools, to predict responses to ENV105 effectively. This diagnostic will be crucial in guiding patient selection for further clinical trials, specifically Phase 3.
Looking Ahead in Oncology
The partnership between Kairos Pharma and PreCheck Health Services symbolizes a significant advancement in addressing urgent medical needs in oncology. By focusing on personalized treatment solutions, they aim to transform how cancer, particularly resistant forms, are managed.
Dr. Neil Bhowmick, the Chief Scientific Officer of Kairos Pharma, highlighted the potential impact of this collaboration by stating, "Leveraging PreCheck’s vast experience in genetic testing provides a considerable advance in the development of our therapies. The integration of their expertise will significantly enhance our ability to identify patients who will benefit from ENV105."
In a similar vein, Dr. John Yu, the CEO, expressed enthusiasm about the partnership: "Working with PreCheck Health Services marks an exciting step forward for Kairos Pharma. We are enhancing our commitment to deliver personalized cancer treatment solutions. Our aim is to use the biomarkers we develop to ensure effective and tailored therapies for each patient."
About Kairos Pharma and PreCheck Health Services
Kairos Pharma Ltd. operates at the leading edge of oncology, focusing on overcoming challenges associated with drug resistance through innovative treatments. Their work, which includes a diverse range of investigational therapies, represents a commitment to improving patient outcomes and reshaping cancer management.
PreCheck Health Services is recognized for its expertise in genetic sequencing and precision diagnostics. Their capabilities in supporting personalized medicine are vital as the two organizations work collaboratively to pave the way for more effective cancer treatments, especially targeting resistant forms of disease.
Frequently Asked Questions
What is the primary goal of the partnership between Kairos Pharma and PreCheck Health Services?
The goal is to develop biomarkers to identify patients who will best respond to the cancer therapy ENV105, improving targeting of treatment for prostate and lung cancer patients.
What are the clinical trials involved in this collaboration?
The two key trials are NCT05401110, focused on EGFR-driven lung cancer, and NCT05534646, targeting castrate-resistant prostate cancer.
How will biomarkers improve cancer treatment?
Biomarkers will enable more precise patient selection for therapies, increasing the likelihood of successful treatment outcomes by tailoring therapies to individual patient profiles.
What role do companion diagnostics play in cancer treatment?
Companion diagnostics are critical tools that help determine which patients are most likely to benefit from specific therapeutic products, guiding their inclusion in clinical trials.
What is the expected impact of this collaboration on oncology?
This partnership aims to personalize cancer treatment, particularly for patients facing resistance, thereby significantly improving their treatment outcomes.
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