Innovative ONCO Prime Platform Spotlighted by Ryvu Therapeutics
Ryvu Therapeutics Unveils ONCO Prime Platform for Cancer Research
Ryvu Therapeutics, a forward-thinking clinical-stage drug discovery company, is excited to showcase its novel ONCO Prime platform at a prominent global summit focused on RAS therapies. This platform is designed to identify synthetic lethal targets through the use of innovative patient-derived primary cell cultures. The ensuing insights from this groundbreaking approach have unveiled potential new drug targets, particularly in KRAS-mutant colorectal cancer, underscoring its broad applicability in various tumor types.
Key Presentation at the RAS-Targeted Drug Development Summit
During this year's 6th Annual RAS-Targeted Drug Development Summit, Krzysztof Brzózka, the Chief Scientific Officer, will provide a detailed presentation on the ONCO Prime platform. This summit gathers leading experts and scientists focused on RAS therapeutic strategies, creating an avenue for extensive collaboration.
Understanding the ONCO Prime Platform
This advanced platform utilizes new cancer models that strike an optimal balance between translational potential and high-throughput capabilities. By harnessing patient-derived cells, ONCO Prime integrates a wealth of medical histories with genomic, transcriptomic, and histopathological data to correlate clinical outcomes with molecular insights. Initial results demonstrate the platform's capability to uncover perhaps overlooked drug targets in KRAS-mutant colorectal cancer, with ongoing screenings tailored towards various tumor types.
Insights from Ryvu's Leadership
Sharing insights on the platform, Krzysztof Brzózka remarked, "We are pleased with the rapid development and the novel targets identified in KRAS-mutant cells, targets that traditional immortalized cell lines have frequently bypassed. This achievement is a testament to the unique capabilities of our platform, and we look forward to engaging with the international community on these significant findings." This highlights the potential shifts in therapeutic strategies that ONCO Prime may present.
Support and Funding for ONCO Prime
The ONCO Prime project is supported by funding from the European Union under the Operational Programme European Funds for Modern Economy for 2021-2027. The initiative aims to pave new pathways for personalized cancer therapies through sophisticated approaches based on patient-derived primary cultures and extensive omics characterization. With an anticipated PLN 26.3 million (approximately USD 6.6 million) earmarked for the project, Ryvu Therapeutics is set to make significant advancements in its research efforts.
The Importance of the RAS-Targeted Drug Development Summit
As a vital forum dedicated to RAS discovery, the 6th Annual RAS-Targeted Drug Development Summit plays an essential role in the evolution of cancer therapies. More than 150 influential leaders in RAS-focused research will convene, sharing knowledge and strategizing on how to create effective RAS therapies that can lead to improved outcomes for patients globally.
About Ryvu Therapeutics
Founded in 2007 and headquartered in Kraków, Ryvu Therapeutics has established itself as a leader in drug discovery and development, particularly in the realm of small-molecule therapies targeting emerging oncology challenges. The company has developed a robust pipeline that employs diverse therapeutic mechanisms and is known for its innovative approach to cancer biology.
Ryvu's flagship program, RVU120, is a selective CDK8/CDK19 kinase inhibitor showing promise for treating hematologic malignancies and solid tumors, currently advancing through Phase II clinical trials. The company's dedication to partnering with leading global organizations, like BioNTech and Exelixis, exemplifies its commitment to innovation in cancer treatment.
Frequently Asked Questions
What is the ONCO Prime platform?
ONCO Prime is a cutting-edge drug discovery platform by Ryvu Therapeutics that identifies novel synthetic lethal targets using patient-derived primary cell cultures.
What potential does ONCO Prime have in treatment?
The platform has revealed novel drug targets, especially in KRAS-mutant colorectal cancer, but also has a promising application across various tumor types.
Who will present at the RAS-Targeted Drug Development Summit?
Krzysztof Brzózka, the Chief Scientific Officer of Ryvu Therapeutics, will be presenting details about the ONCO Prime platform during the event.
How is the ONCO Prime platform funded?
The project is co-financed by the European Union as part of their Operational Programme European Funds for Modern Economy and is set to receive substantial grant funding.
When did the ONCO Prime platform development start?
The platform development began in mid-2023, and within a short span, significant discoveries have been made, demonstrating its effectiveness.
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