Emergent BioSolutions Secures $67.4M for TEMBEXA to Combat Smallpox
Emergent BioSolutions Expands Commitment to Smallpox Preparedness
Emergent BioSolutions Inc. (NYSE: EBS) has recently taken a significant step in bolstering national health security by securing two contract options valued at $67.4 million. These contracts will allow the procurement of additional treatment courses of TEMBEXA (brincidofovir), a crucial antiviral medication aimed at COVID-19 preparedness against potential outbreaks of smallpox.
The Importance of TEMBEXA
TEMBEXA is specifically indicated for the treatment of human smallpox disease affecting both adults and pediatric patients, including the most vulnerable neonates. The strategic procurement will aid the U.S. government's ongoing efforts to prepare for public health emergencies related to smallpox, a disease eradicated in the 1970s but still considered a serious threat due to its potential for biological warfare and accidental release.
Comments from Emergent Leadership
Paul Williams, Senior Vice President of Products Business at Emergent BioSolutions, stated, "This announcement underscores our longstanding partnership with the U.S. government, demonstrating our commitment to meeting the country’s preparedness needs for smallpox and related threats. We are eager to continue delivering TEMBEXA to support this critical program."
Contractual Details and Future Potential
This recent order from the U.S. government exercises procurement options CLIN0004A and CLIN0005A under an existing 10-year agreement. This contract has a maximum value of up to $568 million, highlighting the key role that TEMBEXA plays in the nation's health strategy. The secured funding will remain active through 2027, ensuring a steady supply of the antiviral to combat smallpox effectively.
Government Funding and Support
This initiative is significantly supported by federal funds from various health agencies, including the Department of Health and Human Services and the Biomedical Advanced Research and Development Authority (BARDA). This partnership is crucial for maintaining public health readiness against possible smallpox threats.
Understanding TEMBEXA: Mechanism and Usage
TEMBEXA is an oral antiviral approved by the FDA in June 2021 to treat smallpox disease caused by the variola virus. It is available in 100 mg tablets and a 10 mg/mL oral suspension, making it accessible for patients with varying health conditions. The oral suspension is particularly vital for patients who may struggle to swallow pills, making it a versatile option in therapeutic settings.
What Patients Should Know
While TEMBEXA is crucial for treating smallpox, it is vital for patients and healthcare providers to be aware of its limitations. The medication is not indicated for other diseases, and its effectiveness in humans has not been conclusively tested due to ethical constraints surrounding human smallpox exposure. Caution is advised, especially for immunocompromised patients who may experience reduced efficacy from the treatment.
Supporting Public Health Initiatives
Emergent BioSolutions remains dedicated to innovation in public health, addressing urgent health needs with advanced solutions. Their portfolio includes a wide range of vaccines and therapeutics developed to combat serious public health threats. By securing this contract, Emergent is reinforcing its mission to protect and enhance life through preparedness and prevention.
A Look Ahead
As the landscape of public health continues to evolve, the commitment of Emergent BioSolutions to enhance national and global health security through strategic partnerships and innovative solutions is invaluable. The company’s ongoing investment in products like TEMBEXA demonstrates a proactive approach to addressing potential bioterrorism threats and ensuring robust public health measures are in place.
Frequently Asked Questions
What is TEMBEXA used for?
TEMBEXA is used for the treatment of smallpox disease in adults and pediatric patients, including neonates.
How much was the recent contract for TEMBEXA?
The recent contract secured by Emergent BioSolutions is valued at $67.4 million.
What government agency supports the procurement of TEMBEXA?
The procurement is supported by the Department of Health and Human Services and BARDA.
Is TEMBEXA effective for other diseases?
No, TEMBEXA is specifically indicated for treating smallpox and is not effective against other diseases.
What are the potential side effects of TEMBEXA?
Common side effects include diarrhea, nausea, and vomiting. Further details can be found in the prescribing information.
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